WEBINAR
Proteomics-Driven Discovery in Retinal Disease: A Case Study in Drug Repurposing
Discover how omics analysis enabled drug repurposing insights for mutation-independent treatment of retinal diseases using Omics Playground.
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Mohamed Ali Jarboui
Sr. Scientist & Project Manager
CFMP, University Hospital Tübingen
Axel Martinelli
Head of Biology
BigOmics Analytics
About
Inherited retinal diseases like retinitis pigmentosa (RP) often lack effective treatments that work regardless of genetic mutation. In this webinar, Dr. Mohamed Ali Jarboui will showcase how researchers from the Eye Clinic at University of Tübingen used the Omics Playground platform to uncover promising, mutation-independent therapeutic pathways targeting protein homeostasis: a strategy with strong potential for drug repurposing.
Join us for an interactive walkthrough of a study that demonstrated how pharmacological inhibition of VCP, a central regulator of protein quality control, can drive long-lasting photoreceptor protection in distinct RP models. Through advanced proteomics and metabolomics analysis, the team identified conserved neuroprotective mechanisms that transcend specific mutations, revealing actionable insights for treating retinal degeneration.
This session is a must-attend for life science professionals seeking to explore:
- How omics-driven insights accelerate drug discovery and repurposing
- Real-world application of proteomics and systems biology in therapeutic development
- How analysis platforms like Omics Playground streamline and scale translational research
Learn how data-driven approaches can reveal new therapeutic angles and offer fresh hope in the fight against retinal diseases.
Speakers
Dr. Mohamed Ali Jarboui is a senior scientist and project manager at the Core Facility for Medical Proteomics (CFMP), University Hospital Tübingen, Germany. He specializes in mass spectrometry–based proteomics and multi-omics integration for clinical and translational research. His work focuses on protemics application in precision medicine.
He is actively involved in designing and optimizing end-to-end workflows for LC-MS based clinical proteomics, from sample preparation and method development to data analysis and biological interpretation, with the goal of translating complex omics data into actionable insights for diagnostics and therapy guidance.
Dr. Axel Martinelli is Head of Biology at BigOmics Analytics, a Swiss startup building intuitive platforms for omics data visualization and analysis. He holds a Ph.D. in molecular biology and a Master in bioinformatics. His research background spans parasitic genomics at the Wellcome Trust Sanger Institute and malaria-focused studies as an Assistant Professor at Hokkaido University. At BigOmics, he bridges lab and computational expertise to make advanced omics analysis accessible to researchers worldwide.
About Omics Playground
Omics Playground is user-friendly centralized data discovery platform for RNA-Seq and proteomics data that allows you to store and interactively visualize data from your experiments.
- Easy-to-use and interactive solution
With more than 100 HQ plots for your publications - Unified biodata management & analytics
With highly interactive dashboards in more than 18 modules - Robust and reproducible results
Best-in class algorithm and co-analysis with more than 6000 public dataset - Analytics anywhere. Anytime
The cloud-based platform allows you to share data with your collaborators 24/7
