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Category: Scientific Insights

brain in neurodegenerative diseases studies
Scientific Insights

Insights into Neurodegenerative Diseases using Transcriptomics Datasets

Insights into Neurodegenerative Diseases using Transcriptomics Datasets A re-analysis of the similarities and differences between Alzheimer’s disease and Parkinson’s disease. Published on June 27th, 2023By Axel Martinelli What are Neurogenerative …

RNA-seq transcriptome analysis of artisunate with Omics Playground
Scientific Insights

RNA-seq transcriptome analysis of the anti-inflammatory effect of artesunate on cerebral malaria

RNA-seq transcriptome analysis of the anti-inflammatory effect of artesunate on cerebral malaria Published on April 25th, 2023⏱ 11 min read RE-ANALYSIS Cerebral malaria is the main cause of death in …

Differentially expressed proteins in the KEGG proteasome pathway following PFN1 overexpression.
Scientific Insights

Profilin 1 and its role in proteasome inhibitors resistance

Browsing through the most recent proteomics dataset on the public PRIDE database, I came across this study (PXD033148) from Wang and colleagues at Xiangya Hospital of Central South University in …

Re-analysis of the transcriptomic data from a recently published article on the role of osteopontin on prostatic fibrosis and inflammation.
Scientific Insights

The Role of Osteopontin on Prostatic Fibrosis and Inflammation

The Role of Osteopontin on Prostatic Fibrosis and Inflammation Published on January 19th, 2022 by Axel Martinelli For this post, I will re-analyse the transcriptomic data from a recently published …

The role of the microbiome on social interactions in mice
Scientific Insights

The role of the microbiome on social interactions in mice

The original article by Stilling et al (2018), described the association between gut microbiome composition and social behaviour in mice. They compared the social interaction of germ-free mice (GF, devoid …

Aging Insights from the GTEx Tissue Collection
Scientific Insights

Insights into Aging from the GTEx Tissue Collection

The Genotype-Tissue Expression program (GTEx) is an extensive collection of gene expression profiles from 54 different tissue sites across more than 1000 individuals. This data can provide various insights on …

IL-17A as a potential therapeutic target for osteoarthritis
Scientific Insights

IL-17A as a possible therapeutic target for Osteoarthritis

IL-17A as a possible therapeutic target for Osteoarthritis Published on July 8th, 2021by Axel Martinelli For this brief article, I have decided to re-analyse the RNA-seq data from a recently …

Glucocorticoid Resistance in Multiple Myeloma: a Dataset Re-analysis
Scientific Insights

Glucocorticoid Resistance in Multiple Myeloma: a Dataset Re-analysis

Glucocorticoid Resistance in Multiple Myeloma: a Dataset Re-analysis Published on April 28th, 2021 For this post, I decided to re-analyse a dataset from a recent article by Logie et al …

Scientific Insights

Re-analysis of the first public SARS-CoV-2 transcriptomics data

Part 1. The first public SARS-CoV-2 transcriptome from Blanco-Melo et. al. is now available and we took the opportunity to upload it onto our Omics Playground platform for analysis. The …

Scientific Insights

Finding Potential Biomarkers And Therapeutic Drugs With Coronavirus Datasets

We recently launched the Viromics Playground, an open-access online version of the Omics Playground platform that includes over 200 viral infection transcriptomes. I thought it might be a good idea …

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