RE-ANALYSIS Cerebral malaria is the main cause of death in patients infected with Plasmodium falciparum. Artemisinin and its derivatives, such as artesunate (ATN), are the first-line treatment prescribed for severe …
This short guide is meant for biologists with little or no coding or bioinformatic experience and no access to a bioinformatician. It is not meant to be comprehensive, but rather …
Browsing through the most recent proteomics dataset on the public PRIDE database, I came across this study (PXD033148) from Wang and colleagues at Xiangya Hospital of Central South University in …
For this post, I will re-analyse the transcriptomic data from a recently published article on the role of osteopontin on prostatic fibrosis and inflammation (Popovics et al, 2021). Fibrosis occurs …
The original article by Stilling et al (2018), described the association between gut microbiome composition and social behaviour in mice. They compared the social interaction of germ-free mice (GF, devoid …
The analysis of omics data involves the collaboration of biologists and bioinformaticians. They need each other to generate the data and analyse it. Biologists have a deep understanding of the …
The Genotype-Tissue Expression program (GTEx) is an extensive collection of gene expression profiles from 54 different tissue sites across more than 1000 individuals. This data can provide various insights on …
For this brief article, I have decided to re-analyse the RNA-seq data from a recently published paper on the osteoarthritis-like (OA-like) transcription changes induced in response to Interleukin-17 (IL-17) (Mimpen …
Amidst the talks of personalised medicine, it is easy to forget that cheap large-scale genome sequencing is a recent phenomenon that started in the early 2000’s with the development of …
For this post, I decided to re-analyse a dataset from a recent article by Logie et al (2021) using our Omics Playground platform. Multiple Myeloma (MM) is a malignancy that …
